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Inhibitors of protein–protein interactions (PPIs): an analysis of scaffold choices and buried surface area

Ran, Xu; Gestwicki, Jason E

Current opinion in chemical biology. Volume 44: (2018, June); pp 75-86 -- Elsevier

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Aim for the core: suitability of the ubiquitin-independent 20S proteasome as a drug target in neurodegeneration

Opoku-Nsiah, Kwadwo A.; Gestwicki, Jason E.

Translational research: the journal of laboratory and clinical medicine. Volume 198: (2018, August); pp 48-57 -- Elsevier

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Revisiting the ``Art of the Chemical Probe''

Schwarz, Daniel M. C.; Gestwicki, Jason E.

ACS chemical biology. Volume 13:Number 5 (2018); pp 1109-1110 -- American Chemical Society

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Expanding the Number of 'Druggable' Targets: Non‐Enzymes and Protein–Protein Interactions

Makley, Leah N.; Gestwicki, Jason E.

Chemical biology & drug design. Volume 81:Number 1 (2013, January); pp 22-32 -- John Wiley & Sons, Ltd

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Specific Binding of Tetratricopeptide Repeat Proteins to Heat Shock Protein 70 (Hsp 70) and Heat Shock Protein 90 (Hsp90) Is Regulated by Affinity and Phosphorylation

Assimon, Victoria A.; Southworth, Daniel R.; Gestwicki, Jason E.

Biochemistry -- American Chemical Society -- Volume: 54 48; (pages 7120-7131) -- 2015

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Targeting Hsp90/Hsp70-Based Protein Quality Control for Treatment of Adult Onset Neurodegenerative Diseases

Pratt, William B.|Gestwicki, Jason E.|Osawa, Yoichi|Lieberman, Andrew P.

annual review of pharmacology and toxicology -- Annual Reviews, Inc. -- Volume: 55 (pages 353-372) -- 2015

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A model in which heat shock protein 90 targets protein-folding clefts: Rationale for a new approach to neuroprotective treatment of protein folding diseases

Pratt, William B et al.

Experimental biology and medicine. Volume 239:Number 11 (2014, November); pp 1405-1413 -- SAGE Publications

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Selective Targeting of Cells via Bispecific Molecules That Exploit Coexpression of Two Intracellular Proteins

Dunyak, Bryan M. et al.

ACS chemical biology -- American Chemical Society -- Volume: 10 11; (pages 2441-2447) -- 2015

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Concise synthesis of spergualin-inspired molecules with broad-spectrum antibiotic activity1

Assimon, Victoria A. et al.

MedChemComm: rapid communication of research in medicinal chemistry. Volume 6:Issue 5 (2015, May); pp 912-918 -- Royal Society of Chemistry

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A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis

Moss, Steven M. et al.

Cell host & microbe. Volume 25:Number 3 (2019, March 13th); pp 454-462.e6 -- Elsevier Inc., Cell Press Imprint

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