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A prion-like mechanism for the propagated misfolding of SOD1 from in silico modeling of solvated near-native conformers.

PloS one, 2017, Vol.12(5), p.e0177284 [Peer Reviewed Journal]

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Diverse expression of selected SMN complex proteins in humans with sporadic amyotrophic lateral sclerosis and in a transgenic rat model of familial form of the disease.

PloS one, 2014, Vol.9(8), p.e104614 [Peer Reviewed Journal]

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Structural and functional analysis of human SOD1 in amyotrophic lateral sclerosis.

PloS one, 2013, Vol.8(12), p.e81979 [Peer Reviewed Journal]

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An indicator cell assay for blood-based diagnostics.

PloS one, 2017, Vol.12(6), p.e0178608 [Peer Reviewed Journal]

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SALS-linked WT-SOD1 adopts a highly similar helical conformation as FALS-causing L126Z-SOD1 in a membrane environment.

Biochimica et biophysica acta, September 2016, Vol.1858(9), pp.2223-2230 [Peer Reviewed Journal]

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Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis.

Biochimica et biophysica acta, August 2014, Vol.1842(8), pp.1295-1301 [Peer Reviewed Journal]

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Metal-free ALS variants of dimeric human Cu,Zn-superoxide dismutase have enhanced populations of monomeric species.

PloS one, April 9, 2010, Vol.5(4), p.e10064 [Peer Reviewed Journal]

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Colocalization of 14-3-3 proteins with SOD1 in Lewy body-like hyaline inclusions in familial amyotrophic lateral sclerosis cases and the animal model.

PloS one, 2011, Vol.6(5), p.e20427 [Peer Reviewed Journal]

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The effects of the cellular and infectious prion protein on the neuronal adaptor protein X11α.

Biochimica et biophysica acta, November 2015, Vol.1850(11), pp.2213-2221 [Peer Reviewed Journal]

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Intracerebroventricular injection of encapsulated human mesenchymal cells producing glucagon-like peptide 1 prolongs survival in a mouse model of ALS.

PloS one, 2012, Vol.7(6), p.e36857 [Peer Reviewed Journal]

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