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Structural insight into the molecular mechanism of allosteric activation of human cystathionine β-synthase by S-adenosylmethionine.

Proceedings of the National Academy of Sciences of the United States of America, September 16, 2014, Vol.111(37), pp.E3845-E3852 [Peer Reviewed Journal]

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Structural basis of regulation and oligomerization of human cystathionine β-synthase, the central enzyme of transsulfuration.

Proceedings of the National Academy of Sciences of the United States of America, October 1, 2013, Vol.110(40), pp.E3790-E3799 [Peer Reviewed Journal]

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Rescue of cystathionine beta-synthase (CBS) mutants with chemical chaperones: purification and characterization of eight CBS mutant enzymes

The Journal of biological chemistry, 21 May 2010, Vol.285(21), pp.15866-73 [Peer Reviewed Journal]

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Domain Organization, Catalysis and Regulation of Eukaryotic Cystathionine Beta-Synthases

PLoS ONE, 2014, Vol.9(8) [Peer Reviewed Journal]

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The role of surface electrostatics on the stability, function and regulation of human cystathionine β-synthase, a complex multidomain and oligomeric protein

BBA - Proteins and Proteomics, September 2014, Vol.1844(9), pp.1453-1462 [Peer Reviewed Journal]

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Effect of the disease-causing R266K mutation on the heme and PLP environments of human cystathionine β-synthase.

Biochemistry, August 14, 2012, Vol.51(32), pp.6360-6370 [Peer Reviewed Journal]

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Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe.

Angewandte Chemie (International ed. in English), April 22, 2013, Vol.52(17), pp.4641-4644 [Peer Reviewed Journal]

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Enzyme replacement with PEGylated cystathionine β-synthase ameliorates homocystinuria in murine model

The Journal of clinical investigation, 01 June 2016, Vol.126(6), pp.2372-84 [Peer Reviewed Journal]

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Pharmacokinetics and pharmacodynamics of PEGylated truncated human cystathionine beta-synthase for treatment of homocystinuria

Life Sciences, 01 May 2018, Vol.200, pp.15-25 [Peer Reviewed Journal]

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Pharmacokinetics and pharmacodynamics of PEGylated truncated human cystathionine beta-synthase for treatment of homocystinuria

Life Sciences, May 1, 2018, Vol.200, p.15 [Peer Reviewed Journal]

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by this Author/Contributor:

  1. Majtan, Tomas
  2. Majtan, T
  3. Kraus, Jan P.
  4. Kraus, J.P.

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