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Synthesis and c-Met kinase inhibition of 3,5-disubstituted and 3,5,7-trisubstituted quinolines: identification of 3-(4-acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7- (trifluoromethyl)quinoline as a novel anticancer agent.

Journal of medicinal chemistry, April 14, 2011, Vol.54(7), pp.2127-2142 [Peer Reviewed Journal]

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Discovery of 3H-imidazo[4,5-b]pyridines as potent c-Met kinase inhibitors: design, synthesis, and biological evaluation.

ChemMedChem, June 2012, Vol.7(6), pp.1057-1070 [Peer Reviewed Journal]

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SAR of amino pyrrolidines as potent and novel protein-protein interaction inhibitors of the PRC2 complex through EED binding.

Bioorganic & medicinal chemistry letters, April 1, 2017, Vol.27(7), pp.1576-1583 [Peer Reviewed Journal]

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Synthesis and biological evaluation of 2-amino-5-aryl-3-benzylthiopyridine scaffold based potent c-Met inhibitors.

Bioorganic & medicinal chemistry, November 1, 2013, Vol.21(21), pp.6804-6820 [Peer Reviewed Journal]

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The application of click chemistry in the synthesis of agents with anticancer activity

Drug Design, Development and Therapy, 2015, Vol.9, pp.1585-1599 [Peer Reviewed Journal]

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The anti-hepatocellular carcinoma cell activity by a novel mTOR kinase inhibitor CZ415.

Biochemical and biophysical research communications, June 3, 2017, Vol.487(3), pp.494-499 [Peer Reviewed Journal]

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Design, synthesis and evaluation of 6-aryl-indenoisoquinolone derivatives dual targeting ERα and VEGFR-2 as anti-breast cancer agents.

European journal of medicinal chemistry, August 8, 2016, Vol.118, pp.328-339 [Peer Reviewed Journal]

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Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.

Bioorganic & medicinal chemistry letters, March 1, 2006, Vol.16(5), pp.1191-1196 [Peer Reviewed Journal]

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by this Author/Contributor:

  1. Wang, Ying
  2. Wang, Y.
  3. Chen, Yi
  4. Ai, Jing
  5. Geng, Meiyu

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