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Ketones and lactate increase cancer cell “stemness,” driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via Metabolo-Genomics

Cell Cycle, 15 April 2011, Vol.10(8), p.1271-1286 [Peer Reviewed Journal]

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Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: Visualizing the therapeutic effects of metformin in tumor tissue

Cell Cycle, 01 December 2011, Vol.10(23), p.4047-4064 [Peer Reviewed Journal]

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Molecular profiling of a lethal tumor microenvironment, as defined by stromal caveolin-1 status in breast cancers

Cell Cycle, 01 June 2011, Vol.10(11), p.1794-1809 [Peer Reviewed Journal]

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The reverse Warburg Effect: Glycolysis inhibitors prevent the tumor promoting effects of caveolin-1 deficient cancer associated fibroblasts

Cell Cycle, 15 May 2010, Vol.9(10), p.1960-1971 [Peer Reviewed Journal]

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Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells

Cell Cycle, 15 August 2010, Vol.9(16), p.3276-3296 [Peer Reviewed Journal]

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The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

Cell Cycle, 01 September 2010, Vol.9(17), p.3485-3505 [Peer Reviewed Journal]

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Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the “reverse Warburg effect”: A transcriptional informatics analysis with validation

Cell Cycle, 01 June 2010, Vol.9(11), p.2201-2219 [Peer Reviewed Journal]

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Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: Implications for breast cancer and DCIS therapy with autophagy inhibitors

Cell Cycle, 15 June 2010, Vol.9(12), p.2423-2433 [Peer Reviewed Journal]

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Autophagy in cancer associated fibroblasts promotes tumor cell survival: Role of hypoxia, HIF1 induction and NFκB activation in the tumor stromal microenvironment

Cell Cycle, 01 September 2010, Vol.9(17), p.3515-3533 [Peer Reviewed Journal]

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HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment-specific oncogenesis

Cell Cycle, 01 September 2010, Vol.9(17), p.3534-3551 [Peer Reviewed Journal]

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by this Author/Contributor:

  1. Pavlides, Stephanos
  2. Pavlides, S.
  3. Lisanti, Michael P.
  4. Sotgia, Federica
  5. Martinez-Outschoorn, Ubaldo E.

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