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The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndrome.

The Journal of biological chemistry, July 19, 2013, Vol.288(29), pp.20817-20829 [Peer Reviewed Journal]

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Impact of environmental enrichment on neurogenesis in the dentate gyrus during the early postnatal period

Brain Research, 30 September 2011, Vol.1415, pp.23-33 [Peer Reviewed Journal]

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CB1 cannabinoid receptors increase neuronal precursor proliferation through AKT/glycogen synthase kinase-3beta/beta-catenin signaling.

The Journal of biological chemistry, March 26, 2010, Vol.285(13), pp.10098-10109 [Peer Reviewed Journal]

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Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome.

PloS one, 2013, Vol.8(4), p.e61689 [Peer Reviewed Journal]

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Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome

Neuroscience, 01 October 2016, Vol.333, pp.277-301 [Peer Reviewed Journal]

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Dietary restriction differentially protects from neurodegeneration in animal models of excitotoxicity

Brain Research, Mar 26, 2004, Vol.1002(1-2), pp.162-166 [Peer Reviewed Journal]

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CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells

BBA - Gene Regulatory Mechanisms, November 2012, Vol.1819(11-12), pp.1173-1185 [Peer Reviewed Journal]

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Early-occurring proliferation defects in peripheral tissues of the Ts65Dn mouse model of Down syndrome are associated with patched1 over expression

Laboratory Investigation, 2012, Vol.92(11), p.1648 [Peer Reviewed Journal]

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Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome.

The Journal of neuroscience : the official journal of the Society for Neuroscience, June 30, 2010, Vol.30(26), pp.8769-8779 [Peer Reviewed Journal]

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Prenatal pharmacotherapy rescues brain development in a Down's syndrome mouse model.

Brain : a journal of neurology, February 2014, Vol.137, pp.380-401 [Peer Reviewed Journal]

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by this Author/Contributor:

  1. Ciani, Elisabetta
  2. Ciani, E.
  3. Bartesaghi, Renata
  4. Bartesaghi, R
  5. Trazzi, Stefania

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