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Far-infrared rays control prostate cancer cells _in vitro_ and _in vivo_

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  • Title:
    Far-infrared rays control prostate cancer cells _in vitro_ and _in vivo_
  • Author: Hiroki Shima ; Shingo Yamamoto ; Jun Qiu ; Mayumi Shincho ; Seiichi Hirota ; Yoshie Yoshikawa ; Reigetsu Yoshikawa ; Tomoko Hashimoto-Tamaoki
  • Subjects: Cancer
  • Description: We introduce a new effective method to control hormone refractory prostate cancer cells by using an activated rubber/resin form (RB), far-infrared ray emitter, with or without sodium butyrate (SB). The growth of three human prostate cancer cell lines (Du145, PC-3 and LNCaP) was suppressed _in vitro_ and _in vivo_ by using RB, and the cells were eradicated with RB + 3 mM SB. G1 arrest and apoptotic pathway proteins were induced by RB with intensified expressions of apoptosis - related mRNA on cDNA microarray. RB radiates far-infrared rays of the 4 to 25 [mu]m wavelengths to an object which exert a favorable influence on a cancer control. These results may render us a new therapeutic modality in hormone refractory prostate cancer.
  • Creation Date: 2009

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