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Preparation method of 3-sulfinyl indole derivative

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  • Title:
    Preparation method of 3-sulfinyl indole derivative
  • Author: Zhang Yuhong ; Sang Peng
  • Subjects: Chemistry ; Metallurgy ; Organic Chemistry ; Heterocyclic Compounds ; Medicine ; Sciences ; Chemistry ; Chemistry
  • Language: Chinese;English
  • Description: The invention discloses a preparation method of a 3-sulfinyl indole derivative. The method comprises the following steps: adding alkali, an oxidant, an indole compound and aryl disulfide diphenyl into an organic solvent; heating to 80-100 DEG C; completely reacting; and conducting post-treatment to obtain the 3-sulfinyl indole derivative. The preparation method of the 3-sulfinyl indole derivative disclosed by the invention is easy to operate, simple in post-treatment and strong in primer designability. Compounds in required structures can be designed and synthesized according to actual demands, and the practicality is stronger. Meanwhile, the compound prepared by the method is good in biological activity, can be used as a raw material to synthesize various 3-sulfinyl indole compounds, and has higher economic values.
  • Creation Date: 11 September 2013

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