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The impact of isatin derivatives on antibiotic production by Streptomyces hygroscopicus CH-7

Hemijska Industrija, 01 January 2016, Vol.70(2), pp.123-128 [Peer Reviewed Journal]

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  • Title:
    The impact of isatin derivatives on antibiotic production by Streptomyces hygroscopicus CH-7
  • Author: Ćirić Jovan T ; Konstantinović Sandra S ; Ilić Slavica B ; Gojgić-Cvijović Gordana ; Savić Dragiša S ; Veljković Vlada B
  • Found In: Hemijska Industrija, 01 January 2016, Vol.70(2), pp.123-128 [Peer Reviewed Journal]
  • Subjects: Isatin Derivatives ; Streptomyces Hygroscopicus ; Hexaene H-85 ; Azalomycine ; Economics
  • Language: English
  • Description: The effect of isatin derivatives as a nitrogen source on antibiotic (Hexaene H-85 and Azalomycine B) production by Streptomyces hygroscopicus CH-7 was studied. Isatin-3-hydrazone, 5-chloroisatin-3-hydrazone, isatin-3-tosylhydrazone, 5-chloroisatin-3-tosylhydrazone, isatin-3-(4`-hidroxy)benzoilhydrazone and 5-chloroisatin-3-(4`-hidroxy)benzoilhydrazone were synthesized in a crude glycerol, obtained during the biodiesel production from edible sunflower oil. The highest concentration of Hexaene H-85 is achieved with 5-chloroisatin-3-hydrazone (197 mg/cm3) in medium, while isatin-3-hydrazone has a greatest impact on Azalomycine B production (72 μg/cm3). [Projekat Ministarstva nauke Republike Srbije, br. III 45001]
  • Identifier: ISSN: 0367-598X ; E-ISSN: 2217-7426 ; DOI: 10.2298/HEMIND141127019C

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