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Decline in Literacy and Incident AD Dementia Among Community-Dwelling Older Persons

Yu, Lei et al.

Journal of aging and health. Volume 30:Number 9 (2018); pp 1389-1405 -- Sage Publications

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  • Title:
    Decline in Literacy and Incident AD Dementia Among Community-Dwelling Older Persons
  • Author: Yu, Lei;
    Wilson, Robert S.;
    Han, S. Duke;
    Leurgans, Sue;
    Bennett, David A.;
    Boyle, Patricia A.
  • Found In: Journal of aging and health. Volume 30:Number 9 (2018); pp 1389-1405
  • Journal Title: Journal of aging and health
  • Subjects: Geriatrics--Periodicals; Older people--Health and hygiene--Periodicals; aging--domain-specific literacy--AD dementia--mild cognitive impairment; Dewey: 618.97
  • Rights: legaldeposit
  • Publication Details: Sage Publications
  • Abstract:

    Objective:To quantify longitudinal change in financial and health literacy and examine the associations of declining literacy with incident Alzheimer's disease (AD) dementia and mild cognitive impairment (MCI).Method:Data came from 799 participants of an ongoing cohort study. Literacy was measured using a battery of 32 questions. Clinical diagnoses were made annually following uniform structured procedures. The associations of declining literacy with incident AD dementia and MCI were tested using a joint model for longitudinal and time-to-event data.Results:We observed an overall decline in total literacy score over up to 6 years of follow-up ( p < .001). Faster decline in literacy was associated with higher risks for incident AD dementia (hazard ratio = 4.526, 95% confidence interval = [2.993, 6.843], p < .001) and incident MCI (hazard ratio = 2.971, 95% confidence interval = [1.509, 5.849], p = .002).Discussion:Declining literacy among community-dwelling older persons predicts adverse cognitive outcomes and serves as an early indicator of impending dementia.


  • Identifier: System Number: LDEAvdc_100072425854.0x000001; Journal ISSN: 0898-2643; 10.1177/0898264317716361
  • Publication Date: 2018
  • Physical Description: Electronic
  • Shelfmark(s): ELD Digital store

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