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A Retrospective Study of Survivors of Endovascular Coiling for Posterior and Anterior Aneurysms

Wilson, Sarah J. et al.

Medicine. Volume 94:Issue 32 (2015, August 8th) -- Lippincott, Williams & Wilkins

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  • Title:
    A Retrospective Study of Survivors of Endovascular Coiling for Posterior and Anterior Aneurysms
  • Author: Wilson, Sarah J.;
    Drackford, Ruth;
    Holt, Michael;
    Anser, Azim.
  • Found In: Medicine. Volume 94:Issue 32 (2015, August 8th)
  • Journal Title: Medicine
  • Subjects: Médecine--Périodiques; Periodicals; Medicine--Periodicals; Geneeskunde; Medicine; Dewey: 610.5
  • Rights: legaldeposit
  • Publication Details: Lippincott, Williams & Wilkins
  • Abstract: <x xml:space="preserve">Abstract</x> Abstract

    This article documents the longer-term medical and psychosocial outcomes of patients referred for endovascular coiling.

    There is limited research investigating outcome following endovascular coiling for posterior compared to anterior circulation aneurysms, and minimal understanding of how medical outcomes relate to patient experiences of treatment and quality of life.

    We studied a consecutive cohort of 80 patients referred Australia wide for endovascular coiling between 1995 and 2003 (49% posterior; 76% ruptured; 69% women, mean age 51.5 years). We used a mixed methods approach, assessing medical outcome with the Modified Rankin Scale (MRS) in 61 patients (76%), and health-related quality of life and psychosocial functioning using the EuroQol questionnaire and a qualitative semistructured interview in 49 patients (61%).

    Despite the high proportion of posterior aneurysms, the majority of patients (80%) showed good medical outcomes as indicated by regained independence of activities of daily living (MRS score ⩽3). Patients with unruptured aneurysms were significantly more likely to show good outcomes (P < 0.04), whereas aneurysm location (posterior, anterior, or mixed) showed no significant effect. In patients with good medical outcomes, greater functional disability was associated with neurological complications surrounding treatment (P < 0.05). Good outcomes correlated with higher EuroQol ratings (P < 0.001) and the experience of less change after treatment (P < 0.001), although psychosocial adjustment issues were reported by most of the patients, including those with no medical symptoms.

    These results support the long-term efficacy of endovascular coiling, particularly for posterior circulation aneurysms. They have implications for guiding clinicians and patients in their choice of treatment, as well as the provision of psychological counseling for patient adjustment issues posttreatment.


  • Identifier: ETOClsidyv99be3732; System Number: LDEAvdc_100026420129.0x000001; Journal ISSN: 0025-7974; 10.1097/MD.0000000000001313
  • Publication Date: 2015
  • Physical Description: Electronic
  • Shelfmark(s): ELD Digital store

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