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Heterotypic Ubiquitin Chains: Seeing is Believing

Stolz, Alexandra; Dikic, Ivan

Trends in cell biology. Volume 28:Number 1 (2018, January); pp 1-3 -- Elsevier Science

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  • Title:
    Heterotypic Ubiquitin Chains: Seeing is Believing
  • Author: Stolz, Alexandra;
    Dikic, Ivan
  • Found In: Trends in cell biology. Volume 28:Number 1 (2018, January); pp 1-3
  • Journal Title: Trends in cell biology
  • Subjects: Cytology--Periodicals; Cytology--Research--Periodicals; ubiquitin--heterotypic Ub chain--K11/K48 branched--APC/C--Huntingtin (HTT); Dewey: 571.6
  • Rights: Licensed
  • Publication Details: Elsevier Science
  • Abstract: The biological diversity of ubiquitination resides in the multivalent nature of linkage-specific homotypic and heterotypic ubiquitin (Ub) chains. A recent publication by Yau et al. in Cell describes the development of K11/K48-bispecific antibodies and a physiological role for K11/K48 heterotypic chains in regulation of the cell cycle and clearance of aggregated proteins.
  • Identifier: System Number: ETOCvdc_100067377791.0x000001; Journal ISSN: 0962-8924; 10.1016/j.tcb.2017.11.005
  • Publication Date: 2018
  • Physical Description: Electronic
  • Shelfmark(s): 9049.552000
  • UIN: ETOCvdc_100067377791.0x000001

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