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Vitamin Pharmacogenomics: New Insight into Individual Differences in Diseases and Drug Responses

He, Hai-Yan et al.

Genomics proteomics & bioinformatics -- Elsevier -- Volume: 15 2; (pages 94-100) -- 2017

Online access

  • Title:
    Vitamin Pharmacogenomics: New Insight into Individual Differences in Diseases and Drug Responses
  • Author: He, Hai-Yan;
    Liu, Mou-Ze;
    Zhang, Yue-Li;
    Zhang, Wei
  • Found In: Genomics proteomics & bioinformatics. Volume 15:Number 2(2017); 201704; 94-100
  • Journal Title: Genomics proteomics & bioinformatics
  • Subjects: Genomics; Proteomics; Bioinformatics; Genetics; LCSH: Genomics; LCSH: Proteomics; LCSH: Bioinformatics; LCSH: Genetics; Dewey: 572.86
  • Rights: Licensed
  • Publication Details: Elsevier
  • Abstract: AbstractVitamins are vital to sustain normal physiological function, metabolism, and growth for all living organisms. Being an integral component of coenzyme, vitamins can affect the catalytic activities of many enzymes and the expression of drug transporters. Genetic variations in metabolism and/or transporter genes of drugs can influence the exposure of the human body to drugs and/or their active metabolites, thus contributing to the variations in drug responses and toxicities. Nonetheless,pharmacogenomicsstudies on nutrients have been rarely summarized. In this article, we reviewed recent progress onvitaminpharmacogenomics, for a better understanding on the influence of vitamin-related gene polymorphisms on inter-individual differences in diseases and drug efficacy and safety.
  • Identifier: Journal ISSN: 1672-0229
  • Publication Date: 2017
  • Physical Description: Electronic
  • Shelfmark(s): 4116.314300
  • UIN: ETOCvdc_100044456316.0x000001

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