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Prevalence of Primary Antiretroviral Resistance Trends in Korea

Bang, J. I. et al.

AIDS research and human retroviruses. VOL 24; NUMBER 1, ; 2008, 83-85 -- Mary Ann Liebert, Inc. (pages 83-85) -- 2008

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  • Title:
    Prevalence of Primary Antiretroviral Resistance Trends in Korea
  • Author: Bang, J. I.;
    Song, K. H.;
    Kim, S. H.;
    Cho, J. H.;
    Park, W. B.;
    Park, S. W.;
    Kim, H. B.;
    Kim, N. J.;
    Oh, M. D.;
    Choe, K. W.
  • Found In: AIDS research and human retroviruses. VOL 24; NUMBER 1, ; 2008, 83-85
  • Journal Title: AIDS research and human retroviruses.
  • Subjects: Medicine; Biotechnology; Pharmaceutical Chemistry; LCC: RC607; Dewey: 616.9792
  • Publication Details: Mary Ann Liebert, Inc.
  • Language: English
  • Abstract: Primary drug resistance is an emerging problem in HIV infections. We have investigated the current prevalence of primary resistance in Korea and compared it with previous data. Drug-naive HIV patients attending the outpatient clinic of Seoul National University Hospital between April and August 2006 were enrolled. A medical interview and a genotypic resistance test were performed for each patient. The International AIDS Society-USA Panel consensus statement issued in 2006 was used to define resistance mutations. Eighty-one drug-naive HIV patients were enrolled. Two (2.5%) were infected with primary drug-resistant virus M41L and K103N, respectively. In our previous study, conducted between 1998 and 2002, three (6%) of 50 subjects harbored resistant viruses. Thus the frequency of primary resistance was lower in the present sample than in the earlier one, though the difference is not statistically significant (p = 0.37). In view of our findings, routine antiretroviral resistance tests for drug-naive HIV patients are not obligatory in Korea.
  • Identifier: Journal ISSN: 0889-2229
  • Publication Date: 2008
  • Physical Description: Electronic
  • Accrual Information: Monthly
  • Shelfmark(s): 0773.089000
  • UIN: ETOCRN222084786

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