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Tracheobronchial Neuroendocrine Carcinoma in a Cat

Rossi, G. et al.

Journal of Comparative Pathology VOL 137; NUMBER 2-3, ; 2007, 165-168 -- Elsevier Science B.V., Amsterdam (pages 165-168) -- 2007

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  • Title:
    Tracheobronchial Neuroendocrine Carcinoma in a Cat
  • Author: Rossi, G.;
    Magi, G. E.;
    Tarantino, C.;
    Taccini, E.;
    Mari, S.;
    Pengo, G.;
    Renzoni, G.
  • Found In: Journal of Comparative Pathology VOL 137; NUMBER 2-3, ; 2007, 165-168
  • Journal Title: Journal of Comparative Pathology
  • Subjects: Medicine; Biotechnology; Pharmaceutical Chemistry; LCC: SF; Dewey: 616
  • Publication Details: Elsevier Science B.V., Amsterdam
  • Language: English
  • Abstract: SummaryA tracheobronchial neuroendocrine carcinoma in a 10-year-old cat with a history of coughing, dyspnoea and anorexia is described. Endoscopic examination revealed a yellowish mass protruding into the trachea and partly obstructing the right bronchial lumen. Histological examination of biopsy samples revealed a hypercellular tumour consisting of sheets or ribbons of small hyperchromatic cells, with oval to spindle-shaped nuclei and minimal cytoplasm; nucleoli and mitotic activity were absent. The findings were confirmed on post-mortem examination. The small neoplastic cells were immunolabelled to varying degrees by antibodies against neuron-specific enolase, S-100 protein, synaptophysin and vimentin. Ultrastructural studies revealed scattered neurosecretory granules and scanty cellular junctional complexes, including desmosomes and tonofilaments, in neoplastic cells.
  • Identifier: Journal ISSN: 0021-9975
  • Publication Date: 2007
  • Physical Description: Electronic
  • Accrual Information: Monthly
  • Shelfmark(s): 4962.800000
  • UIN: ETOCRN214664208

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