skip to main content
Show Results with:

Association between adherence to National Comprehensive Cancer Network treatment guidelines and improved survival in patients with colon cancer

Boland, G. M. et al.

Cancer. VOL 119; NUMBER 8, ; 2013, 1593-1601 -- John Wiley & Sons, Ltd Part 8; (pages 1593-1601) -- 2013

Online access

  • Title:
    Association between adherence to National Comprehensive Cancer Network treatment guidelines and improved survival in patients with colon cancer
  • Author: Boland, G. M.;
    Chang, G. J.;
    Haynes, A. B.;
    Chiang, Y. J.;
    Chagpar, R.;
    Xing, Y.;
    Hu, C. Y.;
    Feig, B. W.;
    You, Y. N.;
    Cormier, J. N.
  • Found In: Cancer. VOL 119; NUMBER 8, ; 2013, 1593-1601
  • Journal Title: Cancer.
  • Subjects: Medicine; Biotechnology; Pharmaceutical Chemistry; LCC: RC261; Dewey: 616.994
  • Publication Details: John Wiley & Sons, Ltd
  • Language: English
  • Abstract: AbstractBACKGROUND: The objective of the current study was to examine the impact of adherence to guidelines on stage-specific survival outcomes in patients with stage III and high-risk stage II colon cancer. The National Comprehensive Cancer Network (NCCN) has established working, expert consensus, and evidence-based guidelines for organ-specific cancer care, including care of patients with colon cancer. METHODS: Patients who were diagnosed with colon adenocarcinoma between 1998 and 2002 were selected from within the National Cancer Data Base. The cohort was limited to patients who received their first course of treatment at the reporting facility. Pathologic variables, including tumor depth, lymph node status, and evidence of metastatic disease, were used to restage patients, and the patients were divided into low-risk and high-risk categories on the basis of criteria defined by the NCCN. Relative survival rates were calculated for the entire cohort, stratified according to adherence versus nonadherence to NCCN treatment guidelines. RESULTS: In univariate analysis of treatment adherence patterns for both patient subgroups (high-risk stage II and stage III), several factors were associated with a higher rate of nonadherence in both groups, including older age (P P P CONCLUSIONS: The current study documented practice patterns in a heterogeneous population of patients with colon cancer and demonstrated a survival benefit for patients with stage III and high-risk stage II colon cancer who received treatment that adhered to NCCN guidelines. These data validate the current NCCN practice guidelines for colon cancer and support the concept of guideline-based metrics that can be compared across institutions to assess the quality of cancer care and to compare the quality of cancer care among institutions. Cancer 2013. 2012 American Cancer Society.
  • Identifier: Journal ISSN: 0008-543X
  • Publication Date: 2013
  • Physical Description: Electronic
  • Shelfmark(s): 3046.450000
  • UIN: ETOCRN330287207

Searching Remote Databases, Please Wait